Echocardiographic evaluation of sepsis induced myocardial dysfunction in patients with sepsis or septic shock: a prospective cohort study
نویسندگان
چکیده
Background: Sepsis-induced myocardial dysfunction (SIMD) occurs in 50% of septic patients and is characterized by reduced ejection fraction (EF), cardiac index, impaired contractility, diastolic (DD). In sepsis-induced cardiomyopathy (SICM), EF shows initial significant deterioration on the 1st day, then final improvement at end study. This study evaluated value different parameters measured with trans-thoracic echocardiography (TTE) diagnosis prognosis SIMD surgical intensive care unit (SICU).
 Methodology: prospective cohort was conducted 100 patients, aged from 18 to 50 years admitted SICU being affected sepsis or shock. TTE [EF, tricuspid annular systolic excursion (TAPSE), inferior vena cava (IVC) diameter, E/A ratio grading DD hemodynamic [mean arterial blood pressure (MAP), heart rate (HR), central venous (CVP)] admission, three day post-admission after one week.
 Results: The mortality 45%. found 90%. group had higher DD, HR, lower MAP than surviving group, an insignificant difference LVEF, TAPSE, IVC, CVP 3rd 7th days. (SICM) 31% patients. (grade III highest followed grade I II), HR >110 bpm, < 65mmHg are independent factors that negatively affect duration survival significantly.
 Conclusion: shock vital for prognosis. tachycardia (HR bpm), hypotension (MAP 65mmHg) predictors those Patients SICM (little reversible impairment LV function) a good prognosis.
 Keywords: Sepsis Induced Myocardial Dysfunction, Diastolic dysfunction, Sepsis, Septic Shock
 Preregistration: registered Ethical Committee Faculty Medicine, Tanta University, Tanta, Egypt (approval number: 31728/08/17)
 Abbreviations: SIMD–Sepsis-induced dysfunction; SICM–sepsis-induced cardiomyopathy; TTE– transthoracic echocardiogram. EF–Ejection fraction; DD–diastolic MD–Myocardial TAPSE–tricuspid excursion; SICU–surgical unit
 Citation: El-Oraby MA, Shaban AES, El-Dada AA, El-Badawy AEH. Echocardiographic evaluation induced shock: Anaesth pain 2021;25(2):150-162. DOI: 10.35975/apic.v25i2.1463
 Received: 6 November 2020, Reviewed: 30 December Accepted: 3 February 2021
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ژورنال
عنوان ژورنال: Anaesthesia, pain & intensive care
سال: 2021
ISSN: ['1607-8322', '2220-5799']
DOI: https://doi.org/10.35975/apic.v25i2.1463